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1. Trihydroxymethyl aminomethane for industrial synthesis direction

Because of its simple structure, the central carbon atom is tetrahedral structure, containing three hydroxymethyl and an amino group, which can carry out a variety of substitution and REDOX reactions, is a kind of high quality chemical synthesis raw materials. One of the synthesis methods of the buffer TAPS was made using Tris and 1, 3-propanolone in an alcohol. Usually, the TRIS raw materials used for industrial synthesis do not require high purity of the reagent. The emphasis is on large quantity, so it is more cost-effective to find a raw material manufacturer with large capacity.

2. Trimethylol amino methane for biochemical detection direction

Tris is usually used as a biological buffer to maintain the pH of biochemical reactions. Because of its weak alkalinity, Tris is usually used in combination with acids. It is mainly used for nucleic acid, protein dissolution buffer, protein imprinting buffer, DNA imprinting experiment buffer, DNA agarose gel electrophoresis buffer, etc. In the reaction system because of the involvement of enzymes, proteins and various antibodies, so the buffer requirements are relatively high, so the purchase needs to choose the manufacturer with many years of research and development and production experience, high purity, less impurities to ensure the accuracy of biochemical experiments. Tris buffer temperature effect, easy to absorb carbon dioxide in the air, the configuration of the buffer must be covered tightly sealed.

3. Trimethylol aminomethane for pharmaceutical research and development

Three hydroxymethyl aminomethane another alias, namely trometamol, as do not contain sodium amino buffer base, in the body fluids react with H2CO3, reduce H2CO3, generate HCO32 – again at the same time, can absorb hydrogen ions and correct acidemia, its effect is stronger, and can through the cell membrane, often used in acute metabolic and respiratory acidemia; As an alkaline drug, used for the correction of acidosis without causing increased carbon dioxide retention. Because it is used for pharmaceutical, the whole production of TRIS raw material source, production process route, product purity, impurity ion content are strict requirements, procurement of this kind of products must be very strict and cautious, must pass strict testing.

4. Trimethylaminomethane is used in virus storage fluid

In the virus preservation solution, Tris can first maintain the pH value of the sample, acting as a biological buffer, and the pH buffer range of Tris is: 7.0 to 9.0, the ability to maintain to extract the sample cracking after the release of the stability of the nucleic acid, to avoid the degradation of nucleic acid, and improve the concentration and purity of nucleic acid, guarantee the accuracy of the subsequent operations such as nucleic acid testing analysis, because of special epidemic period, nucleic acid detection requirements, Tris purchase quantity will be bigger, so suggest purchase such products must first buy a small amount of the product before buying large trial confirmed that no problem, also must have technical after-sale to provide professional technical support.


Post time: Feb-24-2021